Fred Flintstone (voiced by Alan Reed): The family patriarch whose schemes backfire.
Wilma Flintstone (voiced by Jean Vander Pyl): Fred's wife, who puts up with his schemes because she nows that no matter what, he has good intentions.
Barney Rubble (voiced by Mel Blanc): Fred's next door neighbor and best friend, who usually gets sucked into Fred's schemes.
Betty Rubble (voiced by Bea Benaderet [1960-1964]/Gerry Johnson [1964-1966]): Barney's wife, who doesn't have much patience for Barney's involvement in Fred's schemes. She is friends with her neighbor, Wilma.
Pebbles Flintstone (voiced by Jean Vander Pyl): Flintstone's daughter who arrived in the third season.
Bamm-Bamm Rubble (voiced by Don Messick): The Rubble's extraordinarily strong infant son..
George Slate (voiced by John Stephenson): Fred's corporate boss.
